Jason Mezey
Assistant Professor
Mapping quatitative loci, pathway modeling, microarray analysis, evo-devo.
Jason Mezey

Phone

607-254-2881
Fax: 607-255-4698

Address

Department of Biological Statistics and Computational Biology
101 Biotechnology Building
Cornell University
Ithaca, NY 14853-2703

Email

Web Sites

Lab Web Site
Department Profile

Background

 

Research Description

Quantitative genetics and genomics, statistical genetics, quantitative trait loci (QTLs), transcriptome modeling, and analysis of microarrays.

Selected Publications

  • Mezey, J.G. and C. Jones (submitted) Coordinated evolution of co-expression clusters in the Drosophila transcriptome. PLOS.
  • Mezey, J.G. (2006) Modularity. Fox, C.W. and J.B. Wolf (eds.) Evolutionary Genetics: Concepts and Case Studies. Oxford University Press.
  • Zelditch, M.L., J.G. Mezey, H.D. Sheets, B.L. Lundrigan and T. Garland (2006)
  • Developmental regulation of skull morphology II: ontogenetic dynamics of
  • covariance. Evolution and Development.
  • Mezey, J.G., D. Houle, and S.V. Nuzhdin (2005) Naturally segregating QTL affecting wing shape of Drosophila melanogaster. Genetics.
  • Mezey, J.G. and D. Houle (2005) The dimensionality of genetic variation for wing shape in Drosophila melanogaster. Evolution.
  • Hahn, M.W., J.G. Mezey, D.J. Begun, J.H. Gillespie, A.D. Kern, C.H. Langley, and L.C. Moyle (2005) Natural Selection and codon bias on single genomes. Nature 433:E5.
  • Wagner, G.P., J.G. Mezey and R. Callabretta (2005) Natural selection and the origin of modules. W. Callebaut and D. Rasking-Gutman (eds.) Modularity: Understanding the Development and Evolution of Natural Complex Systems. MIT Press.
  • Houle, D., J.G. Mezey, P. Galpern, and A. Carter (2004) Automated measurement of Drosophila wings. BMC Evolutionary Biology. 3:25.
  • James, F.C. and J.G. Mezey (2004) Geographic variation in the size and shape of the Savannah Sparrows (Passerculus sandwichensis). The Auk 121:269-270.
  • Wagner, G.P. and J.G. Mezey (2004) The role of genetic architecture constraints for the origin of variational modularity. G. Schlosser and G.P. Wagner (eds.) Modularity in Development and Evolution. Chicago University Press.
  • Mezey, J.G. and D. Houle (2003). Comparing G matrices: why common principal components are informative. Genetics 165:411-425.
  • Houle, D., J.G. Mezey, and P. Galpern (2003) Interpretation of the results of partial common principal components. Evolution 56:433-440.
  • Mezey, J.G., J.M. Cheverud, and G.P. Wagner (2000) Is the genotype-phenotype map modular? An approach using quantitative trait locus (QTL) data. Genetics 156:305-311.
  • Wagner, G.P. and J.G. Mezey (2000) Modeling the evolution of genetic architecture: a continuum of alleles model with pairwise AxA epistasis. Journal of Theoretical Biology 203:163-175.
  • Kim, C., K. Kawasaki, S. Minoshima, C. Amemiya, W. Miller, N. Shimizu, W. Bailey, G.P. Wagner, J.G. Mezey and F. Ruddle (2000) Hox cluster duplication in the horn shark (Heterodontus francisi) and the vertebrate radiation. Proceedings of the National Academy of Sciences 97:1655-1660.
  • Mezey, J.G. and G.P. Wagner (2000) An effect of scale in a non-additive genetic model. Y. Bar-Yam (ed.) Unifying Themes in Complex Systems: Proceedings of the First International Conference on Complex Systems. Perseus Books Group.